Protein Kinase Inhibitors

Protein Kinase Inhibitors: The Promise of Natural Products in Cancer Therapeutics explores a novel therapeutic avenue for cancer treatment through nutraceutical-based kinase inhibitors. This comprehensive resource delves into the scientific mechanisms by which natural products influence kinase activity and disrupt cancer progression, providing valuable insights for researchers, healthcare professionals, and students alike. This book covers the historical background and modern outlook on nutraceuticals, their mechanistic pathways, and clinical aspects of natural CDK inhibitors, highlighting their relevance in cancer therapy. It also examines the potential of polyphenolic derivatives and other natural compounds in inhibiting key kinases involved in major cancer signaling pathways, focusing on their direct application in clinical trials and marketed drugs. Readers will explore topics such as the implications of polyphenols in cancer management, novel sources of breast cancer inhibitors, the role of natural products in lymphoma therapy, and the multitarget potential of phytochemicals. Each chapter is designed to provide a thorough understanding of how natural products can be harnessed to develop innovative cancer therapeutics. This book serves as a valuable resource for academics, scientists, young researchers, students, and pharmacists working or interested in kinase biology and cancer therapeutics. It offers a unique perspective on using nature's own arsenal to combat cancer, bridging the gap between scientific discovery and clinical application, and paving the way for future innovations in structure-based drug design.