Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition

The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed. This is a revised edition of a very successful book, which appeals to both academic and industrial markets. - Illustrates the organic mechanism associated with each enzyme-catalyzed reaction- Makes the connection between organic reaction mechanisms and enzyme mechanisms- Compiles the latest information about molecular mechanisms of enzyme reactions- Accompanied by clearly drawn structures, schemes, and figures- Includes an extensive bibliography on enzyme mechanisms covering the last 30 years- Explains how enzymes can accelerate the rates of chemical reactions with high specificity- Provides approaches to the design of inhibitors of enzyme-catalyzed reactions- Categorizes the cofactors that are appropriate for catalyzing different classes of reactions- Shows how chemical enzyme models are used for mechanistic studies- Describes catalytic antibody design and mechanism- Includes problem sets and solutions for each chapter- Written in an informal and didactic style