Mosaicism in Human Skin : Understanding Nevi, Nevoid Skin Disorders, and Cutaneous Neoplasia

PATTERNS AND MECHANISMS: Mosaicism as a Biological Concept:.- History.- Mosaicism in Plants, Animals, Humans.- Mosaicism Versus Chimerism.- The Mechanisms of Mosaicism .- Genomic Mosaicism of Autosomes.- Epigenetic Mosaicism of autosomes.- Genomic Mosaicism of X Chromosomes.- Epigenetic Mosaicism of X Chromosomes.- The patterns of Mosaicism .- Lines of Blaschko.- Checkerboard Pattern.- Phylloid Pattern.- Patchy Pattern Without Midline Separation.- Lateralization.- Other Patterns, so far Unclassifiable.- MOSAIC SKIN DISORDERS: Nevi.- Melanocytic Nevi.- Other Forms of Pigmentary Mosaicism.- Epidermal Nevi.- Vascular Nevi.- Connective Tissue Nevi.- Nevoid Skin Disorders.- Lyonization (Functional X-Chromosome Mosaicism) in X-Linked Skin Disorders.- Autosomal Non-Nevi.- Neoplastic Skin Lesions.- Benign Tumors.- Malignant Tumors.- CONCLUSION.