Local regional Electro-hyperthermia in patients with liver metastases from colorectal carcinoma.

Introduction: Hyperthermia as an Oncological Therapy Concept - Molecular and immunological effects of hyperthermia on tumour progression and metastasis - General activation of the immune system - Temperature increase above 41C leading to death of tumour cells - Synergy from hyperthermia and chemotherapy and/or radiotherapy - Systemic effects of regional, deep hyperthermia - Physical and technical principles of regional, deep hyperthermia - Definition of Terms - Thermal Dose - Method of regional deep hyperthermia in general and especially in oncothermia - The significance of regional deep hyperthermia within drug tumour therapy - Matched-pair analysis of patients with hepatic metastatic carcinoma of the colon (chemotherapy on the liver with and without regional deep hyperthermia) - Problem Group of patients - Hyperthermia - Chemotherapy - Results - Discussion: Integration of regional deep hyperthermia with oncological treatment concepts - Summary - Bibliography - Appendix (Data sheet)