Frontiers in Leukemia Pharmacotherapy

Frontiers in Leukemia Pharmacotherapy provides a comprehensive overview of the various leukemic disorders found in both children and adults, with an emphasis on current and novel treatment approaches for the healthcare practitioner. By focusing on the unique therapeutic challenges of leukemia, this book aims to meet the diverse needs of physicians, pharmacists, nurses, and other healthcare professionals with an interest in serving patients with leukemia. This comprehensive book is divided into nineteen chapters. Content includes information on specific leukemic disease states in both children and adults. Written by researchers and clinical practitioners, chapters cover a wide array of leukemic topics. Topics include understanding the molecular and genetic basis of acute and chronic leukemia, pharmacology of anti-leukemic agents including traditional chemotherapies, targeted immunotherapy, and tyrosine kinase inhibitors. The epidemiology, etiology, pathogenesis, disease classification, clinical presentation, pathologic features, diagnosis, prognosis, and treatment guidelines for myelodysplastic syndrome, promyelocytic leukemia, pediatric and adult acute and chronic leukemia are other topics covered in more detail. Other topics include: Redox homeostasis occurring in leukemia and the role of antioxidants, supportive care for the leukemic patient experiencing complications from chemotherapy, palliative care for termination of those with leukemia, pharmacometrics using computational modeling to support drug development in leukemia, and future agents that are in clinical trials in our fight against leukemia. Reputable books, journals, monograms, clinical trials, and other resources were used to provide up-to-date medical information useful to assist healthcare professionals in the management of leukemia. Frontiers in Leukemia Pharmacotherapy is an excellent resource for curious healthcare professionals involved in the care of leukemic disorders.