Biological Chemistry of Arsenic, Antimony and Bismuth

Arsenic, antimony and bismuth, three related elements of group 15, are all found in trace quantities in nature and have interesting biological properties and uses. While arsenic is most well known as a poison - and indeed the contamination of groundwater by arsenic is becoming a major health problem in Asia - it also has uses for the treatment of blood cancer and has long been used in traditional chinese medicine. Antimony and bismuth compounds are used in the clinic for the treatment of parasitic and bacterial infections. Biological Chemistry of Arsenic, Antimony and Bismuth is an essential overview of the biological chemistry of these three elements, with contributions from an international panel of experts. Topics covered include:

chemistry of As, Sb and Bibiological chemistry of arsenicbiological chemistry of Sb and Biarsenic and antimony speciation in environmental and biological samplesarsenic in traditional chinese medicinearsenic in aquifersbiomethylation of As, Sb and Biuptake of metalloids by cellsbismuth complexes of porphyrins and their potential in medical applicationsHelicobacter pylori and bismuthmetabolism of arsenic trioxide in blood of the acute promyelocytic leukemia patientsanticancer properties of As, Sb and Biradio-Bi in cancer therapygenotoxicity of As, Sb and Bimetallomics as a new technique for As, Sb and Bimetalloproteomics for As, Sb and Bi Biological Chemistry of Arsenic, Antimony and Bismuth conveys the essential aspects of the bioinorganic chemistry of these three elements, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews. It will find a place on the bookshelves of practitioners, researchers and students working in bioinorganic chemistry and medicinal chemistry.