Advances in Medicine and Biology. Volume 172

Advances in Medicine and Biology. Volume 172 first discusses the advances in formulations for dermal delivery of alpha-tocopherol. Alpha-tocopherol is the major biologically active homolog of vitamin E in human skin, especially the epidermis, and acts as an important antioxidant. Next, the three components that collaboratively engage in the blood epididymal barrier are reviewed, and their individual contribution to protection of the spermatozoa from the immune system is discussed. This compilation includes information regarding the logistics and personal experiences of two separate National Aeronautics and Space Administration (NASA) space missions, Rodent Research-IV and Cell Science-02, as well as for preliminary experiment verification tests and launch simulation testing. Additionally, the authors delve into an International Space Station National Lab Principal investigator's experiences while working with NASA on the aforementioned space biology research projects. The influence of ancestry in pharmacogenomics is discussed from the past to the present, focusing on ethnic distinct populations and how specific mutations observed in these populations may play an important role. The authors explore the way Aeromonas hydrophila has demonstrated involvement in the nutrient cycles of the aquatic environment and may be considered a potential biotechnological tool in biofactory of nanoparticles, bioleaching or bioremediation. The concluding study focuses on rotavirus A, a major pathogen associated with gastroenteritis of children aged under five which contributes to childhood morbidity and mortality in developing countries.